The Department of Defense Serum Repository (DoDSR) was established in 1989 as the Army/Navy Serum Repository for the purpose of storing serum that remained following mandatory HIV testing within the active and reserve components of the Army, Navy, and Marines. Since that time the mission of the serum repository has expanded to include the collection and storage of operational deployment specimens as well as the addition of Air Force specimens. The DoDSR (located in Silver Spring, MD) is a secure facility maintained by the Armed Forces Health Surveillance Center (AFHSC). The DoDSR currently houses over 55 million specimens in large walk-in freezers, and continues to grow by approximately 2.3 million specimens per year.
The mission of the DoDSR is to receive and store remaining serum specimens from HIV testing programs within the DoD, and to receive and store serum specimens related to operational deployments worldwide. The mission of AFHSC includes retaining relevant personnel and other information on individuals serving within the military to include information on serum specimens in the repository. The availability of serial serologic specimens as well as relevant demographic, occupational, and medical information within the databases at AFHSC enables the DoDSR to make significant contributions to clinical and seroepidemiologic investigations.
Specimens contained in the DoDSR are available to researchers and other investigators within the Department of Defense for the purposes of conducting militarily relevant investigations. Access to the specimens is regulated by AFHSC as specified in Appendix 10 of AFHSC Policy Memorandum 2011-05. All questions regarding use of the serum repository should be addressed to the staff of the Armed Forces Health Surveillance Center.